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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12909883888c8a0dcba181e459917ca8f6160e1128cbe577c5ea990cce942054' 
  AND token = '8x2fe9kuX0PbYEInZ3rql9LVK5kwe+hbQv/LuCi7bj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}