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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af8c6a53da453fc42c8d765a191bd3c8cdb013ff5475063ee6b6589bf4940d63' 
  AND token = 'w+tNfaNTjY1SJV2t3jBfesrOZRow1f3JTBRKI1trFIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}