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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ef72b4f9a6d9a8bc2147bbd7737376e9de255fe886c03d9f1c2b9e75f087d0f' 
  AND token = 'AXtCWKM58W2yXcshiDBHGic1ScktSUdvE8MtM0HW6Bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}