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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '995e6d923e121d03b7b6986b794f2723a659e9e5b635454e7e017bb486126d61' 
  AND token = '7Otm6nkstj+v1lu2ZMDzNWgbP2ZEuFiOJCddMjVTTyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}