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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '765953b93c54cde2cf79c66f612ef3837454ac5a228d29d60626f2c5952c0a5b' 
  AND token = 'Uy5gXa2WUNAr7eY3sE1a85lG19Ks3nPCdbDPrLdEt+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}