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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e18c0a47acad02cc8089e86cbcfd425925e559e456d1fb2f062d8d8116fbf91' 
  AND token = '/cgROtcJ1PQnT1xsX4xYIUY/LI33AbnVv5UYtr1Vn08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}