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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44eaf147f68fc3b3e1a7bc361f748cae11b0195263a772117cfa0446e9110bab' 
  AND token = 'qufdnVJIttC/RF812fBTKe6Z769h1MzL07O3wYxipI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}