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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33a31729203688f1c02cec476dba6e6407076ec4df9efa9a445395e44880a76c' 
  AND token = 'MHeM3I2Iggkwbz4sFfiYkaSj19bCIaqZ4/s3JkxsKMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}