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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a02a03b29078c269f35640216bf8fc3d0221c8dc5644e9ba88da96d7b816a2b7' 
  AND token = 'oCB83TuiLx8lSFXBNwJtF/jtoLcEk5ckP2orVj6bUmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}