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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6c69d37b33b2321377fd7accea3601a2c796947809c9b24d29cadbda65a3b67' 
  AND token = 'dy0UYc2FMqFvuq5CWatuq4WpbplzxZLGZGtxgrOSUCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}