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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09971a53ba8f714bbfd5fb80c49385dfddcaf4d5b84c89247c198a763a52eb3a' 
  AND token = 'vTbIT+vYWA/6vUl2fOiHeHNu37ZwKAraP0KMum60vO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}