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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cd2d8372b3e8cdc3a01ac7480957c8de5bc94fa63089d890f446d096cd9a288' 
  AND token = 'Cyl80oUU5AM7VON/oyRUapOSuirkFhD+Bb4hadTM2VI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}