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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '787feb6e5e2651bc6141c3a09669fb2561ec1d6fb64845cdf7c90d8238c14dbf' 
  AND token = '91L/9cmKdu5fegceCrnkLWFUnY6eLWmBeMUXCPayxw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}