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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fe5626c99e90fb0ff421ea7c816b309af8fc181cd3669f493836b9d178e69fb' 
  AND token = 'Z5UkHnXk6iSNJ8pofY3H770z82EtzAUI97G3yZYnEmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}