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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff274c9ec97c04fb0874464db134c7d2b472f717cc5e63e02e07bde1b9daa9b6' 
  AND token = 'gao4GLDFWLDYAyvGq44+Yeu7Zbqf9TcaaSTIaUcH4tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}