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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf9b110db16e450fa0fe7a8a6f54ed2aa9b254d52092b014a433b3fb784a06cd' 
  AND token = 'szJiaD7k0ow5vhpzP+nP66rGeZ2CTdtjtRE7fdr1xvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}