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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27279bd176f7f30f409717acb856c401f64524dfb149a3054857afda42231505' 
  AND token = 'O3W8rBdOlWkCN7CNo6/AfQ3nIUcZbXxC4KiNKDHhlOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}