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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a4e6849e364da81a56820bd4e80587f0bc1b1e693f7b36c7633067a1bcb425e' 
  AND token = 'fTNmHdJiMiP+MzzGvFNHRRaRE4Vj5j9LXPF6qd/VAf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}