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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14a0a9b32c81fccd9aed42451755507a6c4dd81f48d5cf13173a5ae8f2b4a435' 
  AND token = '65rT43XwJLyvHwoteiMM56sJO1HmQYNwxiQl83M6HjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}