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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '019ad2af7358b82ddac93a719b37d615e2ceeda7d9b89ea6b9071e57fb39710f' 
  AND token = 'Iw0xj01xJmSso+olyoz4WUIYmhiBqEKb58ZE3xcP2UI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}