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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e95b9d98ad2516d542e59a95b1d6a6be48cea9a0f89f72cb0aa1086539f16f37' 
  AND token = 'ICz6KA23pSf62wbhDsLgvG7m9KyHnCtalRDLokKyRGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}