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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6083e36e7c75169b43811103e228b4b40b37ebe146238ce10337613915fcf0df' 
  AND token = 'zBgWMKIcCZ/SGMhISC/FIKNV0Un1gThi6WsgQXs/4UQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}