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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fff9da7f15c0789acd40e98e7c410d70c4e759cf26ec1c04a862216203f89a5e' 
  AND token = 'zawncsAOoM40HxIPtkUzhnktCQ9XuznVC/qPmBwS8RU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}