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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6226205ef7c6da886ae7f087b749fa41e850f5ca694d0b9e78bbbef4dc35d5a1' 
  AND token = '6YApM1yAJB5b9sZludE2U9Y1DffPveFTasg27mRzZKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}