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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8af3b3d729a9fbb9dd9242cee0eec50185c3930a8e85b93d12b981dcbc1a49d' 
  AND token = 'xs9XifQzp/gpbOyuXWf9sAWts0++SLL5o8FNCaIjWhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}