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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b5e1686f9e4bcfebd7739d2ebd6762c460795d4d867ac00fc3fbb6427eea7a' 
  AND token = 'WPYxFEsdqjX6984D5xFwLu1RMXw5tbvM/2gnpSbn3/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}