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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17b1739af763cfc12bb65774194bc1f1392e13aaa9ca29db81364b2bf5652e25' 
  AND token = 'm1zSAHK5FpH5RZha2kRbi0YUT5+aeBgJtVyFGbcNc14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}