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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c99be83358a1d24b9833e6ced3ec5877a618cb888ce3751be26f6d0a9a406be' 
  AND token = 'HJnfU86dm4MW3JR1eYUhS4cpXUFv63D8fwlSkYpzzh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}