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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '139257aee9bc368856f47dd1e5cbd77ccd57ee580f8feb108357d0f076eaa4f0' 
  AND token = 'XZM5t2gx5rvSI/M/1qKti+wE+cbWU/FMSSu6xEWJCs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}