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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76b7509f464052499726cb049e5031c2b6b89b66790c16ab717e3e646e24c66e' 
  AND token = 'FGX8jevOCskHGSUv8ArtV4t/PXrIDZ4GDyYdjHjxGUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}