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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb1f00fdb656fd5b538dc488ba6df5a6e783ea5ff227361044b8c99a62743427' 
  AND token = 'XOcAa6NyCgsL1mU7HTQWRiE20TzKXLTieMj9hdH1e9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}