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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6efcd5b9dd834c3a0ec789f2f1081aca695d8df85ed2eb66442932f17eb062a2' 
  AND token = 'tCzH2EBTN+mx6KuYH7E/dmo2VoMwTZVTCNKDx+o6QxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}