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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32b037379ed4da2623640a9ef5de03ab34f7410d8790abec7441566ee6bb8a8f' 
  AND token = '1wu+s19PGYkwar2+uggAZybXUix05SJWXdBm2eaLzKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}