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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ea99b1886982b813c5b30bb1c5c5970becf659ab90ee575e4ba9b30af33413a' 
  AND token = 'yEYC97ruyMhXyzUFXZHWppGKES/I2U5L+T0w39V0YnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}