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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c81d252e679ce6c9cd940870d38377900cb9e38e1ee4618152ed518b2d00ac5' 
  AND token = 'A6lNKjHbI5CNfR+R2rH4DTtr0nq/8Hu9ggYHDLz5tTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}