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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '849289ac2430997623b6bdba5c07c6eb5f72a214f1be503c6a8896565cc7cef8' 
  AND token = 'bvWLf4T+QnxgcQx2pW+kHdq9RoMqsfTCiuQ9Qedp4PA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}