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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e036ea85eebc72158ebc5953105d7bdde94079b6d0c2ba9c3d106c4e3b547af6' 
  AND token = 'mPOYz73DxkNr2HomiS+6Uf35lHBAK1xsa4lRm2ZRsuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}