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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3d59a46b9a1ccff79c9a5ec0af3678739bdbee78e37f0a371b972c96958a45d' 
  AND token = 'w3Lwt4Rh86InzJKPfVOC06mbowZtLL5D9sE7Vnq74q4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}