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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '034c5487acf5d2e288115580c49233162496ba1191e2e4b4b504f26f81fa7de0' 
  AND token = 'P7oj2FrYqAWGqxEm7x7nE+lzs9DxYz8Njiyb+h9nmWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}