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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da51a7fa5c7c6fadb78d0d317cb1a4a687f45b2877523006a3c4009233943360' 
  AND token = '1KSF5SMH3drhYfgquNyobyxoL0W3oEd5xhBTrj5wsvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}