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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f8bf9e7233840857dfebd579f8344c468e399b8dc0f59d72f01ab3c2e01b230' 
  AND token = '0PRexdA5APrPEuXUalAl1C/p6DopGd3zChmynPE+SNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}