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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b903bfec61f3a9367b6ed07eb7d8c89c5f959830ba3145454c92fcaa34c7ecd' 
  AND token = 'MQF4Z9TjXu0J0Qzo3paB0kXkFbUvH0ivaVBHDqxXahI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}