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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '648fcef29f286da791dbd1c9132a5e14d0565ec181e4215606c1dfa7fd0acfaf' 
  AND token = 's9QiphxaHyhxrGTBp3YiBiUucqEz2L8SkUXN4+plCSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}