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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ca4d65570ea38644e5f443d22f2488b11c6d73d073799d01db554a94c4038f2' 
  AND token = 'Ryjh5FE07P7g8fn7yEoIJpu6RmYHk2tr3c8qxTpFhJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}