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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39ededa8a59a9a556680f7305dedf9fca15df4cac15c7f0a326d5af52eb0d6b6' 
  AND token = 'YVwk+11i3Kn0zgXOhNoZSIIiSUWUvlr4Sky8xhHn6bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}