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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a1afc4ba4d3692a595272eac73dfa4171e53b87df8b917bd9269e55f3047609' 
  AND token = 'uu6Kcc48gfWQNq7dJdS8MeRo6QfVLlVbAWNPf8NVTpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}