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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1c56aea78d49a648e38030a6ccf83b82b57f963a20ce8ba7a811bc5ca71c65e' 
  AND token = 'gQ0vnXk+Xhzri6Mogah6Am94yVSHd01qtz4Xk/eQraM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}