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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33e7a3f8b73843e8a2256f5a48f3bb42a7cb754d46140cf38c6ae95114893948' 
  AND token = 'vEQ5Ftc66UqbaMt+I0CgWuck5fKLiO9hqUtdkh2qYkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}