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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1c4f077785f4a2d4c865e932e93407eb5b607045c84b999b0c4998f202fb281' 
  AND token = 'skubRfvxAQGgfF/qK3E1FQXC+kQCQ7aA/r5Z6Zu8TQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}