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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15d357ef16b3cb1a72f101b4d82841e26959f5ff5d04c994f4a83a41ded2504a' 
  AND token = 'EKICnoWUkOyJfgQ2zecT0Rw7wkTrbOGqcx90N1s0Lv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}